There is no online example doing the exact thing, but conceptually yes, it's feasible.
Spreadsheet functions are stored in pq_fn property of rowData as shown in this example:
https://paramquery.com/pro/demos/excel_formulayou can add extra column in the table to save Spreadsheet formula corresponding to each column expecting a formula.
When data is posted to remote server, extract formula from pq_fn and save in respective columns.
When data is fetched from the server, add pq_fn property ( containing the formulas ) back to the rowData in json data.